1: Appl Phys B. 2002 Jan;74(1):95-9. 

Detection of biogenic CO production above vascular cell cultures using a
near-room-temperature QC-DFB laser.

Kosterev AA, Tittel FK, Durante W, Allen M, Kohler R, Gmachl C, Capasso F, Sivco
DL, Cho AY.

Rice Quantum Institute, Rice University, Houston, TX 77251-1892, USA.
akoster@rice.edu

We report the first application of pulsed, near-room-temperature quantum cascade
laser technology to the continuous detection of biogenic CO production rates
above viable cultures of vascular smooth muscle cells. A computer-controlled
sequence of measurements over a 9-h period was obtained, resulting in a minimum
detectable CO production of 20 ppb in a 1-m optical path above a standard
cell-culture flask. Data-processing procedures for real-time monitoring of both
biogenic and ambient atmospheric CO concentrations are described.

PMID: 11911164 [PubMed - indexed for MEDLINE]